Background

Jeez, what can you say about Wade Wilson? He's handsome, charming, brilliant and the perfect killing machine. You can say all of the above about him, but only the last part would be true. He's really a disfigured psychopath with no sense of loyalty or restraint. He's also really, really funny.

He had a good old fashioned screwed up childhood. He cant remember if his mother died when he was five or if she beat him as a teenager. His father was either absent completely or killed in a bar fight when Wade was 17. He joined the army and became a mercenary, finding himself to be an exceptional killer. A Canadian, he eventually moved to the US and fell in love with Vanessa Carlysle. Soon after he was diagnosed with cancer and his left his love to prevent her the burden of dealing with a sick loved one. He also has a severe case of mental illness, which makes his behavior unpredictable and erratic. Wade often chats with the voices in his head, much to the confusion of the people around him.

He joined Canada's Department K and was treated with a mutant healing factor to cure the cancer. While the cancer is not gone, the healing factor does keep it in check. The tumors continued to grow, disfiguring his appearance without killing him. Still rebellious, he was killed for insubordination. The healing factor made him all better. From then on, he took odd jobs as a hired killer. He worked for the Kingpin and fought Wolverine among other adventures.

Its always a riot when "The Merc With a Mouth" meets the webbed quipster. He was hired by Sasha Kravinoff before the "Grim Hunt" to keep Spider-Man distracted while Ana Kravinoff kidnapped Mattie Franklin. The wisecracks flew fast and furious between them during the fight, ending in a "Yo Mama" joke contest. For example:

Spider-Man: "Your mother is so ugly that a Skrull tried to copy her during the invasion and died...of ugly." Deadpool: "Your mother is so stupid she tried to get bailout money so she could afford to pay attention."

This goes on for a few pages. He even cracks wise like this while taking on Norman Osborn, whom had intercepted Wilson's communication to Nick Fury from the Skrull mother ship during the invasion. Osborn tried to have Wilson eliminated after the interception but one of the assassins spilled to Deadpool that Norman had hired them. As far as Wade was concerned, since Norman Osborn received the package that he delivered, then Norman Osborn owed him his money.

Deadpool broke into the Avengers Tower (which Osborn was head of after killing the Skrull Queen, using the information sent by Wade) and entertained himself with one of his hallucinations (climbing a bean stalk to face Osborn, who looked like a giant) as he climbed the elevator shaft of the tower. Wilson was eventually fought off by the Thunderbolts, Osborn's personal bodyguards.

Sometime later, Deadpool teamed with Spider-Man to take down one of the most dangerous killers in the mercenary world: Hit-Monkey. Spidey and 'Pool had the usual "confuse the other hero of being the villain" fights before Wilson could tell him that the real killer was a simian.

At another time, Deadpool, Spider-Man and Daredevil worked together to take down the mob and Tombstone.